{"id":1029,"date":"2023-07-05T08:40:29","date_gmt":"2023-07-04T23:40:29","guid":{"rendered":"https:\/\/curated.raq-hiphop.com\/?p=1029"},"modified":"2023-07-05T08:40:29","modified_gmt":"2023-07-04T23:40:29","slug":"rna%e3%82%ac%e3%82%a4%e3%83%89%e3%81%ab%e3%82%88%e3%82%8b%e6%96%b0%e3%81%97%e3%81%84%e9%81%ba%e4%bc%9d%e5%ad%90%e7%b7%a8%e9%9b%86%e3%82%b7%e3%82%b9%e3%83%86%e3%83%a0%e3%81%ae%e9%96%8b%e7%99%ba","status":"publish","type":"post","link":"https:\/\/curated.raq-hiphop.com\/?p=1029","title":{"rendered":"RNA\u30ac\u30a4\u30c9\u306b\u3088\u308b\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u7de8\u96c6\u30b7\u30b9\u30c6\u30e0\u306e\u958b\u767a\u3068\u771f\u6838\u7d30\u80de\u306b\u304a\u3051\u308bRNA\u30ac\u30a4\u30c9DNA\u5207\u65ad\u9175\u7d20\u306e\u767a\u898b\uff08AASJ\uff09"},"content":{"rendered":"

from AASJ<\/a><\/p>\n

CRISPR\/Cas\u306a\u3057\u3067\u306f\u8003\u3048\u3089\u308c\u306a\u3044\u307b\u3069\u91cd\u8981\u306a\u751f\u547d\u79d1\u5b66\u306e\u4e00\u90e8\u3068\u306a\u3063\u3066\u3044\u308b\u306e\u304c\u3001RNA\u30ac\u30a4\u30c9\u306b\u3088\u308aCas\u5206\u5b50\u3092\u30b2\u30ce\u30e0\u306e\u7279\u5b9a\u306e\u5834\u6240\u306b\u30ea\u30af\u30eb\u30fc\u30c8\u3067\u304d\u308b\u6280\u8853\u3067\u3059\u3002\u3053\u306e\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001Cas9\u306a\u3069\u306e\u5206\u5b50\u3060\u3051\u3067\u306a\u304f\u3001RNA\u3092\u542b\u3080\u69d8\u3005\u306a\u6a19\u7684\u3092\u7de8\u96c6\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308a\u3001\u65b0\u3057\u3044Cas\u6d3b\u6027\u3092\u63a2\u3059\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n

2021\u5e74\u306b\u306f\u3001TnpB\u3068\u3044\u3046\u5206\u5b50\u304c\u7279\u5b9a\u3055\u308c\u3001RNA\u3092\u30ac\u30a4\u30c9\u3068\u3057\u3066\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u3059\u308b\u5206\u5b50\u306e\u5b58\u5728\u304c\u78ba\u8a8d\u3055\u308c\u3001\u7814\u7a76\u304c\u9032\u5c55\u3057\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u6771\u5927\u30fb\u6fe1\u6728\u3055\u3093\u306e\u7814\u7a76\u5ba4\u306b\u3088\u3063\u3066\u89e3\u8aad\u3055\u308c\u305fTnpB\u306e\u69cb\u9020\u306f\u3001CRISPR\/Cas\u3088\u308a\u3082\u3088\u308a\u30b3\u30f3\u30d1\u30af\u30c8\u306a\u907a\u4f1d\u5b50\u7de8\u96c6\u30b7\u30b9\u30c6\u30e0\u304c\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

MIT\u306eBroad\u7814\u7a76\u6240\u304b\u3089\u306e\u8ad6\u6587\u3067\u306f\u3001TnpB\u306b\u4f3c\u305f\u5206\u5b50\u304c\u771f\u6838\u7d30\u80de\u3067\u3082\u5b58\u5728\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u5206\u5b50\u306fRNA\u30ac\u30a4\u30c9\u3092\u4f7f\u7528\u3057\u3066\u907a\u4f1d\u5b50\u7de8\u96c6\u3092\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u3001\u305d\u306e\u69cb\u9020\u3068\u6a5f\u80fd\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u7814\u7a76\u3067\u306f\u3001Fz\u5206\u5b50\u3068\u547c\u3070\u308c\u308b\u5206\u5b50\u304c\u7279\u5b9a\u3055\u308c\u3001\u771f\u6838\u751f\u7269\u3084\u5de8\u5927\u30a6\u30a4\u30eb\u30b9\u304c\u30b3\u30fc\u30c9\u3059\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002TnpB\u3084Cas12\u306a\u3069\u3068\u6bd4\u8f03\u3057\u306a\u304c\u3089\u3001\u3053\u308c\u3089\u306e\u5206\u5b50\u304cRNA\u306b\u30ac\u30a4\u30c9\u3055\u308c\u308bDNA\u5207\u65ad\u9175\u7d20\u3067\u3042\u308b\u3053\u3068\u304c\u69cb\u9020\u7684\u306b\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3055\u3089\u306b\u3001\u9175\u6bcd\u306eFz1\u5206\u5b50\u306b\u7126\u70b9\u3092\u5f53\u3066\u3066\u3001Fz1\u304c\u5207\u65ad\u3059\u308bDNA\u306e\u7279\u7570\u914d\u5217\u3092\u8a8d\u8b58\u3059\u308b\u30ac\u30a4\u30c9\u3068\u3057\u3066\u50cd\u304f\u30ce\u30f3\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0RNA\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u3082\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u308c\u3089\u306e\u89e3\u6790\u3092\u5143\u306b\u3001Fz1\u3092\u7528\u3044\u3066\u4eba\u9593\u306e\u7d30\u80de\u306e\u30b2\u30ce\u30e0\u7de8\u96c6\u304c\u53ef\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001Fz1\u86cb\u767d\u8cea\u3068\u30ac\u30a4\u30c9\u3001TAM\u3001\u6a19\u7684DNA\u306e\u69cb\u9020\u89e3\u6790\u304c\u8a73\u3057\u304f\u884c\u308f\u308c\u3001\u6700\u3082\u30b3\u30f3\u30d1\u30af\u30c8\u3067\u52b9\u7387\u306e\u9ad8\u3044\u907a\u4f1d\u5b50\u7de8\u96c6\u304c\u53ef\u80fd\u306aFz1\u304c\u4f5c\u6210\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u3053\u306e\u7814\u7a76\u306e\u7d50\u679c\u306f\u975e\u5e38\u306b\u8208\u5473\u6df1\u304f\u3001\u7279\u7570\u6027\u304c\u9ad8\u304f\u30aa\u30d5\u30bf\u30fc\u30b2\u30c3\u30c8\u306e\u5207\u65ad\u304c\u5c11\u306a\u3044\u305f\u3081\u3001\u65b0\u3057\u3044\u907a\u4f1d\u5b50\u7de8\u96c6\u30b7\u30b9\u30c6\u30e0\u3068\u3057\u3066\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u771f\u6838\u7d30\u80de\u306bRNA\u30ac\u30a4\u30c9DNA\u5207\u65ad\u9175\u7d20\u304c\u767a\u898b\u3055\u308c\u305f\u3053\u3068\u306f\u3001\u30b2\u30ce\u30e0\u9032\u5316\u306e\u7406\u89e3\u306b\u3082\u91cd\u8981\u306a\u8ca2\u732e\u3092\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n

\n

*Disclamer:\u672c\u30ad\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u306fAASJ<\/a>\u304b\u3089\u30d4\u30c3\u30af\u304a\u3088\u3073\u81ea\u52d5\u751f\u6210\u3055\u308c\u307e\u3057\u305f\u3002\u6b63\u78ba\u306a\u5185\u5bb9\u3084\u8a73\u7d30\u3092\u77e5\u308a\u305f\u3044\u65b9\u306f\u30ea\u30f3\u30af\u5148\u306e\u5143\u30b3\u30f3\u30c6\u30f3\u30c4\u3092\u3054\u89a7\u304f\u3060\u3055\u3044\u3002<\/p>\n

+ \u30ad\u30e5\u30ec\u30fc\u30b7\u30e7\u30f3\u5143\u306e\u8a18\u4e8b\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

from AASJ CRISPR\/Cas\u306a\u3057\u3067\u306f\u8003\u3048\u3089\u308c\u306a\u3044\u307b\u3069\u91cd\u8981\u306a\u751f\u547d\u79d1\u5b66\u306e\u4e00\u90e8\u3068\u306a\u3063\u3066\u3044\u308b\u306e\u304c\u3001RNA\u30ac\u30a4\u30c9\u306b\u3088\u308aCas\u5206\u5b50\u3092\u30b2\u30ce\u30e0\u306e\u7279\u5b9a\u306e\u5834\u6240\u306b\u30ea\u30af\u30eb\u30fc\u30c8\u3067\u304d\u308b\u6280\u8853\u3067\u3059\u3002\u3053\u306e\u6280\u8853\u306e\u9032\u6b69\u306b\u3088\u308a\u3001Cas9\u306a\u3069\u306e\u5206\u5b50\u3060 […]<\/p>\n","protected":false},"author":2,"featured_media":65,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[21,12,11],"tags":[],"class_list":["post-1029","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-aasj","category-medical","category-science"],"jetpack_featured_media_url":"https:\/\/curated.raq-hiphop.com\/wp-content\/uploads\/2023\/05\/curated.png","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=\/wp\/v2\/posts\/1029","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1029"}],"version-history":[{"count":0,"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=\/wp\/v2\/posts\/1029\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=\/wp\/v2\/media\/65"}],"wp:attachment":[{"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1029"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1029"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/curated.raq-hiphop.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1029"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}